The Journal

Treating PMOS requires supporting both cellular metabolic pathways and gut health simultaneously. Insulin sensitivity doesn't happen in isolation—it is deeply tied to your gut microbiome.

To maintain energy, protect lean muscle mass, and keep digestion comfortable, your meal plan must prioritise nutrient density over volume. As high as 25% to 33% of weight lost during GLP-1 therapy can come from lean muscle tissue rather than fat. Muscle tissue dictates your baseline metabolic rate, making daily protein intake your highest priority.